Next generation sample preparation for cryo-EM based on Spotiton
지금까지의 Cryo-EM의 bottleneck인 다량의 sample 사용, 수작업의 grid 준비,
최적의 ice thickness 형성의 어려움 등을 한번에 해결할 수 있습니다.
Grid에 sample spotting parameter를 camera로 지속적으로 monitoring 함으로써
재현성 있는 실험을 수행할 수 있으며 good quality의 grid 선택이 가능합니다.
blot-free high speed plunging Self-wicking grids allow rapid on-the-fly dispensing to reduce air water interface effects and
potentially address preferred orientation, aggregation or denaturation effects
automated grid handling Precise and controlled movement of grids eliminates manual damage and loss
on-board optical grid screening Accept or reject grids ahead of EM screening based on visual images of likely grid quality
intuitive automated workflows Guided workflows provide easy set-up, use and cleaning of the instrument for even novice users
sample tracking and recording Capture all relevant parameters and grid images for record keeping and future reproducibility
cryogen level sensing/temperature control Ensure stability and quality of cryogens while safely kept in an automated drawer