PRODUCT

NUGEN

(주)엠디엑스케이는 고객의 연구 목적에 적합한 기술과 서비스를 제공합니다.

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Brand

Superior performance and simple work
flows for a broad range of sample types

NuGEN은 Technology는 whole tissue, FFPE, single cell 및 liquid biopsy sample 등
광범위한 sample type에서 RNA 및 DNA를 추출하는 sample prep product 및 다양한
application에 적합한 NGS library prep product를 제공합니다.

Technology

NuGEN은 특화된 Single Primer Enrichment Technology(SPET), Single Primer Isothermal Amplification Technology(SPIA),
그리고 AnyDeplete Technology(formerly InDA-C)등의 기술을 이용하여 whole tissue, FFPE, single cell 및 liquid biopsy sample 등 광범위한 sample type에서
기존의 NGS와 genomic sample preparation의 한계를 극복하고 sequencing과 gene expression의 유용한 데이터를 극대화하여 제공합니다.

Single Primer Enrichment Technology (SPET)

SPET for DNA

Directly enrich regions of DNA for targeted re-sequencing, SNP (SNV) detection, CNV analysis, viral detection, and more.

SPET for RNA

Directly enrich cDNA targets for gene fusion detection and discovery.

유전자 특이적인 probe를 이용하여 관심부위(target region)에 결합시키고 (hybrization & extension) PCR을 통해 원하는 유전자를 증폭합니다.
targeted re-sequencing, SNP (SNV) detection, CNV analysis, viral detection을 수행합니다.
  • High quality or FFPE input
  • Flexible customization from one to thousands of targets
  • Molecular tag for accurate determination of unique molecules
  • Superior alignment, on-target and coverage metrics

Single Primer Isothermal Amplification (SPIA)

Robust cDNA amplification for multiple workflows.

Ribo-SPIA technology를 이용하여 최소 500pg의 total RNA로 부터 쉽고 빠르게 cDNA amplification 가능합니다.
  • Low input RNA-seq and gene expression analysis with microarray and qPCR
  • Pre-amplification for qPCR
  • Whole transcriptome amplification
  • Works with RNA from all sample types–Liquid biopsies, FFPE, LCM, cell lines, tissues
  • Automated workflows available

AnyDeplete (formerly InDA-C)

Stranded RNA-Seq library preparation with targeted transcript depletion.

Gene – specific primer extension으로 Insert Dependent Adaptor Cleavage를 합성함으로써 원하지 않는 RNA를 제거하여 유용한 데이터 만을 얻을 수 있습니다.
  • Customizable to any transcript, any organism
  • Post library depletion avoids off-target mRNA cross-hybridization events that can introduce unwanted bias
  • Maximize informative sequencing reads in whole transcriptome data

Application

  • Quantitation-free, titration-free, dimer-free

  • Modular solutions for any
    application and any organism

  • Directly enrich sequences of interest

  • Methylomics simplified

  • Gene expression for low input samples

  • Bioinformatics Software Solutions

Resources

5mC와 5hmC 분석을 위한 NuGEN Methyl-Seq

PRODUCT INFORMATION 5mC와 5hmC 분석을 위한 Methyl-SeqMethylomics simplified정확한 methylation profiling 분석을..

2018-09-14

NuGEN AnyDeplete technology로 NGS 데이터를 업그레이드 하세요!

PRODUCT INFORMATION AnyDeplete(formerly InDA-C)Gene-specific probe를 이용하여 원하지 않는 RNA를 제거, 유용한 데이터 만..

2018-08-30